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Item Information   Holdings       More by this author     Resnik, Josh     Subjects     Extracorporeal Membrane Oxygenation -- adverse effects     Hemodynamics -- physiology     Cavitation     Pulse     Cardiopulmonary bypass -- Adverse effects     Postoperative Period     MSP Thesis.     Browse Catalog     by author:      Resnik, Josh       by title:      Persistent venous li...         MARC Display

Persistent venous line air at the initiation of cardiopulmonary bypass / by Josh Resnik. by Resnik, Josh Subjects Extracorporeal Membrane Oxygenation -- adverse effects   Hemodynamics -- physiology   Cavitation   Pulse   Cardiopulmonary bypass -- Adverse effects   Postoperative Period   MSP Thesis. Description:  54 leaves : ill. ; 29 cm. Contents:  Thesis advisor: Dr. Ronald Gerrits. Committee members: Dr. Larry Fennigkoh, Mark Simmons. Introduction -- Background -- Materials and methods -- Results -- Discussion -- Conclusion -- A: Raw data. Gaseous microemboli (GME) are potential contributors to significant postoperative morbidity following surgery utilizing cardiopulmonary bypass (CPB). Air present in the venous lines of the extracorporeal circuit prior to the initiation of CPB is one of several possible sources of air entry and GME production. There is currently disagreement among perfusion and surgical communities as to the consequence of venous air prior to the initiation of CPB. This study aimed to investigate whether or not venous line air persists through the venous reservoir, leading to the passage of GME into arterial circulation. In order to measure the ability of a venous reservoir to eliminate air and identify related factors, a circuit was designed to test the effects of air volume, venous reservoir volume, and speed of initiation on embolism passage into the arterial side of the circuit. A range between full liquid and full air was used in the venous lines to study air emboli generation, while increasing reservoir volume and prolonged time of initiation were tested to determine efficacy in reducing embolic load. Linear regression and three-way ANOVA were used to determine statistical significance of effects. Air volume present in the venous line was found to be the most important factor influencing GME generation, showing a linear tread in emboli production with increasing volume. Prolonging time of initiation and increasing reservoir volume significantly reduced embolic counts in a linear fashion across the experimental range, but time had a more powerful effect that occurred quicker.   Copy/Holding information Location Collection Call No. Status   Walter Schroeder Library Master's Theses AC805 .R47 2009 Available Add Copy to MyList Format: HTMLPlain textDelimited Subject:   Email to:

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