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Item Information   Holdings       More by this author     Neuman, Daniel author.     Gerrits, Dr. Ronald, thesis advisor     Kallies, Kirsten     Shimek, Gary     Milwaukee School of Engineering     Subjects     Perfusion (Physiology)     Coronary artery bypass     Medical protocols     MSP Thesis.     Browse Catalog     by author:      Neuman, Daniel author.      Gerrits, Dr. Ronald, thesis advisor      Kallies, Kirsten      Shimek, Gary      Milwaukee School of Engineering       by title:       A review of using h...         MARC Display

A review of using hypoxia as a thereputic modality - developing intermittent hypoxia-hyperoxia conditioning protocol guidelines for surgical CABG patients : a thesis submitted to the faculty of the Milwaukee School of Engineering in partial fulfillment of the requirements for the degree of Master of Science in Perfusion / by Daniel Neuman. by Neuman, Daniel author., Gerrits, Dr. Ronald, thesis advisor, Kallies, Kirsten, Shimek, Gary, Milwaukee School of Engineering [Milwaukee School of Engineering], [ 2019] Subjects Perfusion (Physiology)   Coronary artery bypass   Medical protocols   MSP Thesis. Description:  71 leaves : illustrations, some of which are in color ; 29 cm Contents:  List of Figures -- List of Tables -- Nomenclature -- 1. Introduction -- 2. Background; 2.1 Brief History of Hypoxic Effects on the Body; 2.2 Athletic Benefits of Hypoxic Training; 2.3 Hypoxic Conditioning in the Clinical Setting; 2.4 Need for Clinical Studies on Protocols for Surgical Cardiac Patients; 2.5 Project Statement -- 3. Methods -- 4. Results; 4.1 Finding the Balance of Hypoxic Conditioning; 4.2 Study Design -- 5. Discussion; 5.1 Limitations; 5.2 Future Recommendations -- References -- Appendix A: Mechanisms of Hypoxic Training Adaptations -- Appendix B: Mechanisms of Thereputic Hypoxic Conditioning Adaptation -- Endnotes for Appendices. This document features an exploration of the hormesis effect induced by intermittent hypoxic conditioning (IHC) as a potential thereputic modality for surgical coronary artery bypass graft (CABG) patients. A brief history of IHC is reviewed along with a detailed review of known cellular mechanisms. Various review and primary studies on IHC are examined and show beneficial clinical outcomes for cardiovascular patients. This information is then used to develop protocol guidelines for incorporation of IHC into the clinical management of CABG patients. These guidelines address proper administration, clinical safety, and patient management. Among the findings of this review are that although more research is warranted to fully understand all the mechanisms and to optimize the administration of IHC, this therapy is likely a safe, non-invasive and non-pharmacological treatment that would be a useful aid to current cardiac management and rehabilitation. Form:  text unmediated volume web address:  https://msoe.tind.io/record/970   Copy/Holding information Location Collection Call No. Status   Walter Schroeder Library Master's Theses AC805 .N483 2019 Available Add Copy to MyList Format: HTMLPlain textDelimited Subject:   Email to:

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