MSOE Library Home	Login My List - 0 Help
	Home   Search   My Account

Basic Advanced Power History

Search:  Author KeywordsBarcodeBib No.Call Number Keyword Search (Enter part of a call number -- use wildcards)General Keyword SearchKeyword Search of Contents NotesKeyword Search of Credits Notes (Enter word or words)Keyword Search of FormatKeyword Search of Item DescriptionKeyword Search of Publisher's NameName Keyword SearchPublication Date Keyword SearchSearch Part of an ISBN NumberSearch Part of an ISSN NumberSeries Title KeywordsSubject KeywordsTitle Keywords       Refine Search     > You're searching: Walter Schroeder Library, Milwaukee School of Engineering

Item Information   Holdings       More by this author     Hanson, Kelsey.     Subjects     Platelet-Rich Plasma     Colloids     Wound Healing -- drug effects     Blood -- Transfusion, Autologous     MSP Thesis.     Browse Catalog     by author:      Hanson, Kelsey.       by title:      An in vitro, pilot s...         MARC Display

An in vitro, pilot study to determine the direct antimicrobial effects of platelet gel / Kelsey Hanson. by Hanson, Kelsey. Subjects Platelet-Rich Plasma   Colloids   Wound Healing -- drug effects   Blood -- Transfusion, Autologous   MSP Thesis. Description:  49 leaves : ill. ; 29 cm. Contents:  Thesis advisor: Dr. Ronald Gerrits. Committee members: Matthew Hietpas, Dr. Charles Tritt. Introduction -- Background -- Materials and methods -- Results -- Discussion -- Conclusions. Background: Surgical site infections are a common complication of surgery, and their economic impact is quite large. Platelet gel is used as a new medical procedure that shows promise in lessening the number of surgical site infections. In vivo comparisons of wounds tend to indicate that those treated with platelet gel have fewer infections and heal faster than untreated wounds. Because platelet gel can contain some white blood cells, as well as a number of biologically active molecules, it is reasonable to predict that the platelet gel might have some direct antimicrobial properties. But to date, no publications have investigated this. The goal of this thesis was to examine if platelet gel has any direct antimicrobial effect against four bacteria that are commonly known to cause wound infections. Methods: Four strains of bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa) were plated on a blood agar plate. After 24 hours, platelet gel was prepared and sprayed over the plates of the experimental groups. The plates were then incubated at 37 degrees Celsius and checked at days 1, 2, and 3 to assess growth. Results: At days 1 and 2, there was limited to no growth on the experimental plates of E. faecalis and E. coli. There were some colonies seen on the experimental plates of S. aureus and confluent growth seen on the experimental plates of P. aeruginosa. On day 3, there was confluent growth seen on the experimental plates of E. coli. Conclusion: Platelet gel seems to be an effective antimicrobial agent against certain bacteria. Platelet gel did inhibit, at least to some extent, E. coli, E. faecalis, and S. aureus, but did not seem to retard the growth of P. aeruginosa.   Copy/Holding information Location Collection Call No. Status   Walter Schroeder Library Master's Theses AC805 .H3673 2007 Available Add Copy to MyList Format: HTMLPlain textDelimited Subject:   Email to:

Horizon Information Portal 3.25_9885

© 2001-2013 SirsiDynix All rights reserved.