MSOE Library Home	Login My List - 0 Help
	Home   Search   My Account

Basic Advanced Power History

Search:  Author KeywordsBarcodeBib No.Call Number Keyword Search (Enter part of a call number -- use wildcards)General Keyword SearchKeyword Search of Contents NotesKeyword Search of Credits Notes (Enter word or words)Keyword Search of FormatKeyword Search of Item DescriptionKeyword Search of Publisher's NameName Keyword SearchPublication Date Keyword SearchSearch Part of an ISBN NumberSearch Part of an ISSN NumberSeries Title KeywordsSubject KeywordsTitle Keywords       Refine Search     > You're searching: Walter Schroeder Library, Milwaukee School of Engineering

Item Information   Holdings       More by this author     Anderson, Mark J.     Subjects     Bubbles     Cavitation     Cannula     Cardiopulmonary bypass -- Adverse effects     Blood -- Circulation, Artificial -- Complications.     Extracorporeal Circulation     Fluid mechanics     MSP Thesis.     Browse Catalog     by author:      Anderson, Mark J.       by title:      Further investigatio...         MARC Display

Further investigation into the cavitation equation's ability to predict bubble formation in the cardiopulmonary bypass circuit / by Mark J. Anderson. by Anderson, Mark J. Subjects Bubbles   Cavitation   Cannula   Cardiopulmonary bypass -- Adverse effects   Blood -- Circulation, Artificial -- Complications.   Extracorporeal Circulation   Fluid mechanics   MSP Thesis. Description:  79 leaves : ill. ; 29 cm. Contents:  Thesis advisor(s): Dr. Ronald Gerrits. Committee members: Dr. Charles Tritt, Dr. Larry Fennigkoh. Purpose -- Background -- Materials and methods -- Results -- Discussion -- References -- A: Bubble counter data. Cavitation, the formation of Gaseous Microemboli (GME), is a cause for concern in the field of perfusion due to the risk of neurological damage posed when GMEs form while a patient is on Cardiopulmonary Bypass (CPB). Previous studies have looked for ways to predict cavitation with the goal of enabling perfusionists to decrease the risk for impaired neurological function in patients by limiting the formation of the GMEs while on CPB. In his Master's Thesis, Cameron Bryan developed an equation based on the Bernoulli equation to predict the occurrence of bubble formation in flowing liquid (ơ=(Po-Pv)/[(1/2)*p*V2]). Thomas Grulkowski tested the equation using porcine blood and was unable to verify that Bryan's cavitation equation could accurately predict bubble formation in blood. The goal of this study was to determine if Bryan's cavitation equation could accurately predict the formation of bubbles using sterile water. A normal CPB circuit without an arterial line filter was used to conduct the trials. A Hatteland bubble detector probe was placed at the pump head outlet and set to its most sensitive setting to detect bubble formation. Sterile water was run through the pump at four different flow rates (between 3.5-10.0 L/min) and at two different vacuum pressures (0 and -75 mmHg). Eighty trials were performed. In only one trial did any bubble formation occur, which led to the conclusion that the study could not validate Bryan's cavitation equation as a means for predicting bubble formation in a CPB circuit with sterile water as the perfusate. Possible reasons for the conclusion include lack of nucleatation sites, circuit setup, bubble counter error, bubble collapse and the assumed vapor pressure of sterile water.   Copy/Holding information Location Collection Call No. Status   Walter Schroeder Library Master's Theses AC805 .A44 2007 Available Add Copy to MyList Format: HTMLPlain textDelimited Subject:   Email to:

Horizon Information Portal 3.25_9885

© 2001-2013 SirsiDynix All rights reserved.