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Item Information   Holdings       More by this author     Inman, Laura.     Subjects     Acute renal failure.     Cardiopulmonary bypass -- Adverse effects     MSP Thesis.     Browse Catalog     by author:      Inman, Laura.       by title:      A model of acute ren...         MARC Display

A model of acute renal failure risk following cardiopulmonary bypass at St. Luke's Medical Center, Milwaukee, Wisconsin / Laura Inman. by Inman, Laura. Subjects Acute renal failure.   Cardiopulmonary bypass -- Adverse effects   MSP Thesis. Description:  95 leaves : ill. ; 29 cm. Contents:  Thesis advisor(s): Dr. Charles Tritt. Committee members: Dr. Ronald Gerrits, Dr. Larry Fennigkoh. Introduction -- Background -- Methods -- Results -- Discussion -- Conclusion -- Appendix A- List of variables and categories included for analysis B- Fluid balance equation and fluid balance results. Purpose: Acute renal failure is a serious complication of cardiac surgery utilizing cardiopulmonary bypass. This study aims to develop a risk model for post-operative renal failure. Using this model, the clinician can determine risk of renal failure, and therefore take steps to limit any modifiable actions which may increase this risk. Methodology: This retrospective study examined patients undergoing coronary artery bypass grafting with cardiopulmonary bypass during the period of December 2004 to January 2005 at St. Luke's Medical Center, Milwaukee, Wisconsin. Exclusions were reoperations, concomitant procedures, and preoperative creatinine level greater than 2.0 mg/dl. Forward step logistic regression using the software package SAS was used to develop a model of renal failure risk using pre-determined variables. Major findings: A model was developed to characterize the major risks of postoperative renal failure in the patient population at St. Luke's. Factors which increased risk, in descending order, are: use of pump suction (3.9 odds ratio), creatinine greater than 1.6 mg/dl (3.1), age 70-79 (2.8), age 80 or older (2.7), pump run greater than three hours (2.5), use of loop diuretic on-pump (2.2), peripheral vascular disease (2.1), body mass index greater than 32 (2.0), aprotinin at more than 600 ml, if creatinine is greater than 1.5 (1.9), congestive heart failure (1.8), diabetic on oral medication or insulin (1.6), and 4 or more distal anastamoses (1.3).   Copy/Holding information Location Collection Call No. Status   Walter Schroeder Library Master's Theses AC805 .I56 2006 Available Add Copy to MyList Format: HTMLPlain textDelimited Subject:   Email to:

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