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Item Information   Holdings       More by this author     Brown, Scott M.     Subjects     Heart, Mechanical     Blood -- Circulation, Artificial     Cardiopulmonary bypass -- Adverse effects     MSP Thesis.     Browse Catalog     by author:      Brown, Scott M.       by title:      A model of venous re...         MARC Display

A model of venous return while utilizing vacuum assist during cardiopulmonary bypass / by Scott M. Brown. by Brown, Scott M. Subjects Heart, Mechanical   Blood -- Circulation, Artificial   Cardiopulmonary bypass -- Adverse effects   MSP Thesis. Description:  viii, 61 leaves : ill. ; 28 cm. Contents:  Advisor: Dr. Charles Tritt Committee members: Dr. Ronald Gerrits, Dr. Larry Fennigkoh Introduction -- Background -- Head loss factor -- Venous line configurations -- Wall shear stress -- Cavitation -- Laboratory procedure -- Results -- Analysis -- Conclusions -- References -- Appendices -- A- Blood gas data B- Random number tables C- Measured flow and cannula pressure drop data for the dual - stage cannulas D- Measured flow and cannula pressure drop data for the single - stage cannulas E- Measured bubble counts for the dual - stage and single - stage cannulas F- Predicted data from the model for each cannula G- Statistical powers for the analysis of the bubble count data of each cannula H- t - statistic calculation for the comparison of the model and measured data. In order for vacuum assisted venous return to be used safely and efficiently, a full understanding of venous return is necessary. Through the use of the concepts of conservation of energy and viscous energy dissipation, a theoretical model of venous return utilizing vacuum assist has been developed in this work. The effectiveness and accuracy of this model has been verified through invitro laboratory investigations and statistical analysis. In summary, the developed model accurately predicts flow rates given cannula size, amount of vacuum applied, and circuit dimensions. Although vacuum assisted venous return can provide higher flows through smaller cannula, vacuum assist can lead to increased levels of shear stress that the blood is exposed to as well as an increased likelihood of cavitation in the venous line. Both of which may lead to an exacerbation of the detrimental effects of cardiopulmonary bypass. web address:  https://msoe.tind.io/record/966   Copy/Holding information Location Collection Call No. Status   Walter Schroeder Library Master's Theses AC805 .B769 2000 Available Add Copy to MyList Format: HTMLPlain textDelimited Subject:   Email to:

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