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Walter Schroeder Library, Milwaukee School of Engineering
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Tomich, Angela N.
Subjects
Embolism
Cardiopulmonary bypass -- Adverse effects
Blood -- Circulation, Artificial -- Complications.
MSP Thesis.
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Tomich, Angela N.
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In vitro quantitativ...
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In vitro quantitative analysis of air production with varying base flows / by Angela N. Tomich.
by
Tomich, Angela N.
Subjects
Embolism
Cardiopulmonary bypass -- Adverse effects
Blood -- Circulation, Artificial -- Complications.
MSP Thesis.
Description:
vii, 88 leaves : ill. ; 29 cm.
Contents:
Advisors: Dr. Steven Barnicki, Michael Gough.
Committee members: Dr. Vincent Canino, Dr. Lisa Milkowski.
Introduction -- Purpose -- Variables -- Methods -- Statistical analysis -- Discussion -- Analysis -- Conclusion -- Considerations for future research -- Appendix A: Instructions for authors B: Illustrations of base flow C: CMD-10 Microbubble Detector brochure D: Raw data and regression analysis E: Friedman two-way analysis of variance by ranks F: First order calculations and linear regressions G: Second order calculations H: Matlab calculations.
The main idea of this project was to determine how the production of gaseous microemboli is affected by base flow, and how that relationship is affected by other variables such as hematocrit and membrane oxygenator type. Microemboli can be defined as extremely small air bubbles which can be produced by various methods. If these small air bubbles enter a patient's blood stream, the effects can range from stroke to death, depending upon the quantity and size of the bubbles. The analysis of microbubble population in response to variations in base flow is an idea which is pertinent to perfusion.
This thesis begins with background in cavitation, microair, roller pumps and air production, as well as the processes used to reduce the incidence of air. The experiment, methods and materials used, as well as the ideas behind the idea are then described and illustrated. Statistical analysis, linear regression and second order polynomial evaluation are then discussed in detail with graphs illustrating the results. All raw data and calculations are included in the appendices.
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Walter Schroeder Library
Master's Theses
AC805 .T66 1998
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