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Item Information   Holdings       More by this author     Klees, Theresa, author.     Milwaukee School of Engineering     Subjects     Heart -- Electric properties     Cardiac arrest, Induced     Electrophysiology     Arrhythmia     MSP Thesis.     Browse Catalog     by author:      Klees, Theresa, author.      Milwaukee School of Engineering       by title:      A preliminary study ...         MARC Display

A preliminary study comparing the use of microplegia and del Nido cardioplegia systems and their effects on cardiac electrophysiology : a thesis submitted to the faculty of the Milwaukee School of Engineering in partial fulfillment of the requirements for the degree of Master of Science in Perfusion / by Theresa Klees. by Klees, Theresa, author., Milwaukee School of Engineering Subjects Heart -- Electric properties   Cardiac arrest, Induced   Electrophysiology   Arrhythmia   MSP Thesis. Description:  46 leaves : illustrations, some of which are in color ; 29 cm. Contents:  Introduction -- Background -- Project goal -- Methods -- Results -- Discussion -- Conclusion -- Appendix A: data collection survey -- B: statistical analysis and results. Cardiopulmonary bypass (CPB) has become common practice in most cardiac surgeries today. Often these cases require the cessation of electrical activity accomplished through the use of an aortic cross-clamping and cardioplegia administration. This procedure provides added protection by reducing metabolic activity of the heart while providing a bloodless and motionless field for the surgeon to operate. Currently there are several cardioplegia solutions that can be used during CPB, and there is no consensus as to which is best. The objective of this project was to explore the effects of two cardioplegia solutions, del Nido and microplegia, in their ability to prevent immediate post-surgical arrhythmias. Data were collected via an online survey completed by the perfusionist at Aurora St. Luke's Medical Center at the end of each case, and a statistical analysis was performed. A total of 104 surveys were completed, 50 of which used del Nido and 53 used microplegia. The parameters used to determine adequacy of myocardial protection were the time to return to normal sinus rhythm, whether or not external pacing was required, and if defibrillation was attempted to achieve a normal rhythm after the cross clamp was removed. The findings of this study showed that when del Nido cardioplegia was used, the heart required more time to return to normal rhythm and pacing wires were used more often. It also revealed that when microplegia was used, there was a greater incidence of defibrillation. These results indicate a difference in electrophysiology between the two cardioplegia types with a large incidence of unexplained variability. These results suggest that further study should be completed before adjusting current protocols and practices as this was only a preliminary study to pave the way for a more comprehensive proactive study to determine which type of cardioplegia is superior over the other. Form:  text unmediated volume   Copy/Holding information Location Collection Call No. Status   Walter Schroeder Library Master's Theses AC805 .K547 2015 Available Add Copy to MyList Format: HTMLPlain textDelimited Subject:   Email to:

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