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Item Information   Holdings       More by this author     Bergemann, Michael A.     Milwaukee School of Engineering     Subjects     Cardiopulmonary bypass -- Adverse effects     Acute renal failure -- Prevention     Oxygen -- Physiological transport     Monitoring, Physiologic     Creatinine.     Hematocrit.     MSP Thesis.     Browse Catalog     by author:      Bergemann, Michael A.      Milwaukee School of Engineering       by title:      Retrospective analys...         MARC Display

Retrospective analysis of the effect of intraoperative oxygen delivery on postoperative renal complications : a thesis submitted to the faculty of the Milwaukee School of Engineering in partial fulfillment of the requirements for the degree of Master of Science / by Michael A. Bergemann. by Bergemann, Michael A., Milwaukee School of Engineering Subjects Cardiopulmonary bypass -- Adverse effects   Acute renal failure -- Prevention   Oxygen -- Physiological transport   Monitoring, Physiologic   Creatinine.   Hematocrit.   MSP Thesis. Description:  38 leaves : illustrations ; 29 cm. Contents:  Introduction -- Background -- Methods -- Results -- Discussion -- Conclusions -- References. A common postoperative outcome of patients undergoing cardiac surgery requiring the use of cardiopulmonary bypass (CPB) is acute renal failure (ARF). Acute renal failure is associated with significantly increased mortality, morbidity and healthcare costs; therefore, preventing this condition is of concern. Historically, low intraoperative hematocrit was believed to be one of the most important variables for predicting the postoperative incidence of ARF in CPB patients. Recent studies from a single surgical center, however, have suggested that minimum intraoperative oxygen delivery is a better predictor of ARF in this group. The goal of this study was to further investigate the impact of intraoperative oxygen delivery and intraoperative hematocrit in relation to postoperative ARF and serum creatinine ratios, a traditional measure of the operative insult to the kidneys. A retrospective analysis of 508 coronary artery bypass graft (CABG) patients was conducted using surgical data from Aurora St. Luke's Medical Center in Milwaukee, Wisconsin. The minimum and average delivery of oxygen (ml O2/min/m2) and lowest and average hematocrit (%) for all patients were compared to postoperative ARF diagnosis and serum creatinine ratio. Twenty patients (3.9%) met the criteria for postoperative ARF with significant associations with elevated weight, diabetes, and postoperative blood transfusions. Additionally, elevated serum creatinine ratios associated significantly with elevated weight, diabetes, hypertension, intraoperative blood transfusions, postoperative blood transfusions and average oxygen delivery. The data, however, did not support the hypothesis that minimum delivery of oxygen is a better predictor of ARF compared to lowest hematocrit. Form:  text unmediated volume   Copy/Holding information Location Collection Call No. Status   Walter Schroeder Library Master's Theses AC805 .B457 2014 Available Add Copy to MyList Format: HTMLPlain textDelimited Subject:   Email to:

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