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Walter Schroeder Library, Milwaukee School of Engineering
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Powell, Jayson.
Subjects
Embolism, AIr -- prevention & control
Cardiopulmonary bypass -- Adverse effects
Oxygen -- Physiological transport
Commercial products -- Testing
MSP Thesis.
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Powell, Jayson.
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An assessment of the...
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An assessment of the air handling capabilities of currently available adult oxygenators that contain integrated arterial line filters / by Jayson Powell.
by
Powell, Jayson.
Subjects
Embolism, AIr -- prevention & control
Cardiopulmonary bypass -- Adverse effects
Oxygen -- Physiological transport
Commercial products -- Testing
MSP Thesis.
Description:
82 leaves : ill. ; 29 cm.
Contents:
Thesis advisor: Dr. Ronald Gerrits.
Committee members: Dr. Larry Fennigkoh, Christopher Candek.
Background -- Methods -- Results -- Discussion -- Conclusion -- Appendix A: Trial data -- B: Summaries of data and Johnson transformations -- Minitab v.16 data.
There is a trend among manufacturers of perfusion equipment to produce oxygenators with integrated arterial line filters, such that perfusionists only need to add a single component to their circuit, instead of the traditional two. Any time new components are brought to market, perfusionists are interested in how they handle air emboli that may enter the circuit because of the risk that emboli pose to patients. The goal of this study was to determine the air handling capabilities and characteristics of the three currently available oxygenators with integrated arterial line filters. Each of the three companies producing these products takes a different approach to eliminating emboli from the circulation. The Terumo FX utilizes a fiber bundle with a filter membrane wrapped around it in a single compartment. The Maquet Quadrox-i uses a set of filter cassettes and a hydrophobic membrane to stop and remove particulate and gaseous emboli. The Sorin Synthesis utilizes a more tranditional design with the oxygenator and the arterial line filters residing in separate compartments within the same assembly.
The oxygenators were tested in a circuit built to isolate the oxygenator from other sources of emboli removal. Three channels of data collected volume of air and number of emboli at three locations around the circuit. Each oxygenator was challenged with 10 mL of air in each of 20 trials at two flow and pressure combinations. The trials were divided into groups of 10 and randomly assigned the order in which they would be performed.
The results of the study revealed that the Sorin Synthesis allowed the passage of the most emboli overall, while the Maquet Quadrox-i and the Terumo FX performed similarly. The Maquet Quadrox-i passed a significantly higher volume of air at the higher flow rate and pressure, but not a different number of emboli. Both the Terumo FX and the Sorin Synthesis passed the same volume of air but a decreased number of emboli.
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Walter Schroeder Library
Master's Theses
AC805 .P68 2012
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